Indications:Primary or secondary adrenocortical insufficiency; allergy and anaphylaxis, shock, crohn's disease, ulcerative colitis, rheumatic arthritis, skin disorders and cerebral edema.
Doses & Administrations:
Oral: Adult: 0.5-9mg daily individed doses depending on the disease and response of the patient. Maximum: 15 mg daily. Pediatric: 0.03 - 0.15 mg/kg/day every 6 to 12 hours or 1.5mg/m2 every 6 to 12 hours. Parenteral (I/M or I/V): Adult : 0.5 - 9mg daily in divided dose depending an disease being treated. day by constant I/V infusion after bolus dose of 20 mg. by constant I/V infusion after bolus dose of 20mg. I/M every 6 hours as required for 2-10 days. Pediatric: Neonates : 0.2 - 0.5 mg/kg followed by 0.1 mg/kg po or I/V every 6 to 8 hours. Cerebral edema: 1.5 mg/kg/day every 4 to 6 hours for 5 days. Maximum : 6 mg/kg/day.
Contra Indications: Hypersensitivity to Dexamethasone or other component of the preparation dendritic keratitis, varicella and tuberculosis of the eye.
Precautions:Use cautiously in patients with renal insufficiency, diabetes mellitus, hypertension, osteoporosis, glaucoma, active or latent peptic ulcer, viral infection, tuberculosis; avoid abrupt withdrawal, monitor growth in infants and children who are on iron therapy.
Pregnancy Status:Category "C".
Renal Failure Doses:No dosage adjustment is required.
Lactation Status:Unsafe.
Interactions:Phenytoin, ephedrine, rifampicin, barbiturate may decreased blood level of cortico steroids, avoid use of live virus vaccine. Decrease absorption of calcium and phosphorus, urinary excretion of ascorbic acid, calcium, potassium, zinc, nitrogen. Increase blood glucose, triglycerides, cholesterol. Increase need for B6, Ascorbic acid, folate and vitamin D.
Adverse Effects:
Glucoma cataract formation secondary ocular infection and thinning of the cornea.
Nursing Considerations:
- Monitor baseline body weight, temperature, pulse and respiratory rate. - Monitor fluid balance. - Taper systemic steroid carefully. prolonged sore throat and unusual weight gain. - Monitor Baseline body weight, temperature, Pulse and Respiratory. - Monitor fluid balance. - Taper systemic steroids carefully. - Teach patient to report if stool black/Tarry, Muscle weakness, Prolonged sore throat and unusal weight gain. ---------------------------------------------------------------- IV DILUTION: 0 to 50 mg/ 50 ml...OVER 30 MIN. 51 to 100 mg/ 100 ml IN D5W / NS CAN BE GIVEN BY IV PUSH: Over 1 minute to several min. if dose is < 10 mg.
Doses & Administrations:
Oral: Adult: 0.5-9mg daily individed doses depending on the disease and response of the patient. Maximum: 15 mg daily. Pediatric: 0.03 - 0.15 mg/kg/day every 6 to 12 hours or 1.5mg/m2 every 6 to 12 hours. Parenteral (I/M or I/V): Adult : 0.5 - 9mg daily in divided dose depending an disease being treated. day by constant I/V infusion after bolus dose of 20 mg. by constant I/V infusion after bolus dose of 20mg. I/M every 6 hours as required for 2-10 days. Pediatric: Neonates : 0.2 - 0.5 mg/kg followed by 0.1 mg/kg po or I/V every 6 to 8 hours. Cerebral edema: 1.5 mg/kg/day every 4 to 6 hours for 5 days. Maximum : 6 mg/kg/day.
Contra Indications: Hypersensitivity to Dexamethasone or other component of the preparation dendritic keratitis, varicella and tuberculosis of the eye.
Precautions:Use cautiously in patients with renal insufficiency, diabetes mellitus, hypertension, osteoporosis, glaucoma, active or latent peptic ulcer, viral infection, tuberculosis; avoid abrupt withdrawal, monitor growth in infants and children who are on iron therapy.
Pregnancy Status:Category "C".
Renal Failure Doses:No dosage adjustment is required.
Lactation Status:Unsafe.
Interactions:Phenytoin, ephedrine, rifampicin, barbiturate may decreased blood level of cortico steroids, avoid use of live virus vaccine. Decrease absorption of calcium and phosphorus, urinary excretion of ascorbic acid, calcium, potassium, zinc, nitrogen. Increase blood glucose, triglycerides, cholesterol. Increase need for B6, Ascorbic acid, folate and vitamin D.
Adverse Effects:
Glucoma cataract formation secondary ocular infection and thinning of the cornea.
Nursing Considerations:
- Monitor baseline body weight, temperature, pulse and respiratory rate. - Monitor fluid balance. - Taper systemic steroid carefully. prolonged sore throat and unusual weight gain. - Monitor Baseline body weight, temperature, Pulse and Respiratory. - Monitor fluid balance. - Taper systemic steroids carefully. - Teach patient to report if stool black/Tarry, Muscle weakness, Prolonged sore throat and unusal weight gain. ---------------------------------------------------------------- IV DILUTION: 0 to 50 mg/ 50 ml...OVER 30 MIN. 51 to 100 mg/ 100 ml IN D5W / NS CAN BE GIVEN BY IV PUSH: Over 1 minute to several min. if dose is < 10 mg.
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Unknown - Thursday, 26 May 2011
