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Showing posts with label POTASSIUM CITRATE. Show all posts
Showing posts with label POTASSIUM CITRATE. Show all posts
Monday, 13 June 2011

POTASSIUM CITRATE Indication Doses Contra Indications and Adverse Effects

Indications:

Urinary alkalinizer, when Na Citrate is contraindicated, prevention of uric acid nephrolithiasis and calcium renal stones.

Doses & Administrations:
Administration *dilute adequately with water to minimize gastrointestinal injury * take after meals to avoid saline laxative effect * palatability of oral solution enhanced by chilling ADULT DOSE: FOR URIC ACID STONE: 30 to 60 milliequivalents/day orally in three or four doses with meals or within 30 minutes after meals. ............Mix in 10-30 ml of water or juice................... Maximum daily dosage is 100 milliequivalents PEDIATRIC DOSE: 5-10 mEq after meals and at bed time. NOTE: 1 gm Potassium Citrate = 3.08 mMoles (9.25mEq) Citrate 9.03 mMoles (9.03mEq) potassium

Contra Indications:
Addison's disease, untreated adynamia episodica hereditaria anuria, dehydration, acute heat cramps, hyperkalemia myocardial damage, severe renal impairment with oliguria or azotemia

Precautions:
Monitor serum electrolytes, especially bicarbonate, in patients with renal disease Potassium citrate in patients with decreased urinary output, especially in the presence of hypocalcemia

Pregnancy Status:
CATEGORY "C"

Renal Failure Doses:
CONTRAINDICATED in severe renal impairment, oligouria and azotemia.
Lactation Status:
SAFE

Interactions:
k-SPARING DIURETICS It may cause an increase in toxicity of following drugs: quinine, quinidine, amphetamines, ephedrine. It decreases effectiveness of: lithium, MTX, and tetracyclines.

Adverse Effects:
SERIOUS: alkalosis electrocardiographic abnormalities (associated with hyperkalemia) hyperkalemia

Nursing Considerations:
Use well diluted, chilled solution.Use the solution with in 1 hour of preparation. Watch patient for signs of hyperkalemia, and check bicarbonate levels periodically. Do not administer on an empty stomach.