Analgesics are the drugs that are used to relief pain. There are various kind of drugs used to relieve minor, mild, moderate and severe pains. Two categories of drugs commonly employed as painkillers are;
NSAIDs: Non steroidal anti-inflammatory drugs, these are widely prescribed and also used at OTC painkillers (Examples Diclofenac, Ibuprofen, Meloxicam, Naproxen, Celecoxib etc)
Non-NSAIDs: Paracetamol or acetaminophen, the most extensively used OTC painkiller
It’s important to know that all pain killers have side effects. NSAIDs are known to harm multiple body parts including cardiovascular system, gastrointestinal system, urinary system and blood.
The use of NSAIDs in patients with cardiovascular disease is concerning because of the cardiovascular and gastrointestinal toxicities associated with these agents. Concrete evidence of the safety of NSAIDs in cardiac diseases has not been found. Many studies on the subject are in the pipeline and will be completed in year 2011. The study by Ray and colleagues gives us new and useful information, diclofenac use should be limited in patients with cardiac diseases and naproxen appears relatively safe.
While concluding, still comparatively safe and better alternate to NSAIDs is Paracetamol.
Further Readings:
Solomon, D. H. (2009). “Searching for a safe analgesic in patients with cardiovascular disease.” Circ Cardiovasc Qual Outcomes 2(3): 146-7.
NSAIDs: Non steroidal anti-inflammatory drugs, these are widely prescribed and also used at OTC painkillers (Examples Diclofenac, Ibuprofen, Meloxicam, Naproxen, Celecoxib etc)
Non-NSAIDs: Paracetamol or acetaminophen, the most extensively used OTC painkiller
It’s important to know that all pain killers have side effects. NSAIDs are known to harm multiple body parts including cardiovascular system, gastrointestinal system, urinary system and blood.
The use of NSAIDs in patients with cardiovascular disease is concerning because of the cardiovascular and gastrointestinal toxicities associated with these agents. Concrete evidence of the safety of NSAIDs in cardiac diseases has not been found. Many studies on the subject are in the pipeline and will be completed in year 2011. The study by Ray and colleagues gives us new and useful information, diclofenac use should be limited in patients with cardiac diseases and naproxen appears relatively safe.
While concluding, still comparatively safe and better alternate to NSAIDs is Paracetamol.
Further Readings:
Solomon, D. H. (2009). “Searching for a safe analgesic in patients with cardiovascular disease.” Circ Cardiovasc Qual Outcomes 2(3): 146-7.
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Cardiovascular /
Heart
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Unknown - Wednesday, 11 May 2011
