Indications:
Celecoxib is indicated for the treatment of osteoarthritis, rheumatoid arthritis, acute pain including primary dysmenorrhea, and is also indicated for reducing the number of colon and rectal polyps in familial adenomatous polyposis (FAP). This treatment has NOT been shown to reduce the risk of gastrointestinal cancer or the need for FAP-associated surgeries and routine endoscopic surveillance. Celecoxib is a nonsteroidal anti-inflammatory drug, which selectively inhibits the enzyme, cyclo-oxygenase-2 (COX-2).
Doses & Administrations: Osteoarthritis : 200 mg daily qd or bid Rheumatoid Arthritis : 100-200 mg bid Familial Adenomatous Polyposis: 400 mg bid
Contra Indications:
Hypersensitivity to celecoxib Hypersensitivity to sulfonamides Allergic-type reactions, including asthma and urticaria, to aspirin or nonsteroidal antiinflammatory agents
Pregnancy Status: CATEGORY C
Lactation Status:
UNKNOWN
Interactions:
aspirin fluconazole loop diuretics warfarin
Adverse Effects: Common adverse effects include dyspepsia, diarrhea, and abdominal pain. Although the risk for ulcers and other serious gastrointestinal adverse effects is lower than for other NSAIDs, product labeling still includes warnings about the risk of ulceration, bleeding and perforation.
Nursing Considerations:
Celecoxib taken with a high-fat meal resulted in one to two hour delay in the peak plasma level with an increase in the total absorption of 10% to 20%. Administer with foods
Celecoxib is indicated for the treatment of osteoarthritis, rheumatoid arthritis, acute pain including primary dysmenorrhea, and is also indicated for reducing the number of colon and rectal polyps in familial adenomatous polyposis (FAP). This treatment has NOT been shown to reduce the risk of gastrointestinal cancer or the need for FAP-associated surgeries and routine endoscopic surveillance. Celecoxib is a nonsteroidal anti-inflammatory drug, which selectively inhibits the enzyme, cyclo-oxygenase-2 (COX-2).
Doses & Administrations: Osteoarthritis : 200 mg daily qd or bid Rheumatoid Arthritis : 100-200 mg bid Familial Adenomatous Polyposis: 400 mg bid
Contra Indications:
Hypersensitivity to celecoxib Hypersensitivity to sulfonamides Allergic-type reactions, including asthma and urticaria, to aspirin or nonsteroidal antiinflammatory agents
Pregnancy Status: CATEGORY C
Lactation Status:
UNKNOWN
Interactions:
aspirin fluconazole loop diuretics warfarin
Adverse Effects: Common adverse effects include dyspepsia, diarrhea, and abdominal pain. Although the risk for ulcers and other serious gastrointestinal adverse effects is lower than for other NSAIDs, product labeling still includes warnings about the risk of ulceration, bleeding and perforation.
Nursing Considerations:
Celecoxib taken with a high-fat meal resulted in one to two hour delay in the peak plasma level with an increase in the total absorption of 10% to 20%. Administer with foods
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Unknown - Monday, 30 May 2011
