This is a rare disease and generally happens to one in millions. This genetic disorder is autosomal recessive in nature and affects both women and men. In this disease, the protein that is required to produce fibrin is either missing or is present in fewer amount. Factor XII actually concentrates on how the protein helps in the formation of a clot. People with this deficiency generally do not experience bleeding while undergoing any treatment or surgeries and thus no treatment is required. A low factor XII generally has no medical significance.
A person with this deficiency has no bleeding in major surgeries like genital surgeries etc. In fact, most of the individuals are diagnosed with this deficiency during pre-testing of blood tests before any surgery.
Causes of Factor XII Deficiency
The causes of deficiency of factor XII are unique, for that onee must know the bleeding and clotting process. When bleeding happens, the body initiates a series of reactions that aids the blood clotting process. This series of reaction is termed as coagulation cascade. This process includes special proteins known as coagulation factors. Factor XII is one of the coagulation factors. Each factor in this chain triggers the other reaction and the final product that one gets by this coagulation cascade is the blood clot. Shortage of factor XII restricts bleeding. Hence, blood clot occurs but slowly. This disease is a rare inherited condition and is not fatal.
Symptoms and Treatments
This is not a big medical issue hence generally patient suffering from this disease does not show many symptoms. In addition, since the disease does not harm any body functions, treatment of factor XII is also not necessary. It generally heals by itself.
Diagnostic Tests for Factor XII Deficiency
Diagnosis is made by extended activated partial thromboplastin time (aPTT) test. Factor XII deficiency is detected when blood-clotting examinations are performed for routine testing.
Factor XII Assay: In this test, the blood is drawn from a vein, generally present inside the elbow or in the back portion of the hand. The portion is cleaned with the help of medical antiseptics, to maintain necessary hygiene while testing. An elastic wrapper is draped around the upper arm for the pressure to build up and to produce swelling in the vein. After this, the medical practitioner softly injects a needle in the swollen vein. The blood is collected in an airtight tube that is attached with the inserted needle. Then the elastic band is removed. After the blood is collected, then the needle is also removed and the punctured site is covered to stop excessive bleeding. In case of young children, a pointed tool called lancet can be used to pierce in the skin to make the area bleed. In this case, blood is collected in a small glass tube called pipette, or on slides for testing. A medicated bandage can be used to cover the pierced place to stop the bleeding process.
Partial thromboplastin time (PTT): In this process, a medical practitioner uses needle to take blood from the vein. The blood is collected in an airtight bottle. A bandage is used to cover the bleeding place.
Factor XII deficiency is not a big problem and does not affect any body functions. There is no treatment available, as medical field does not consider it as a dangerous condition unlike other hemic disorders.
A person with this deficiency has no bleeding in major surgeries like genital surgeries etc. In fact, most of the individuals are diagnosed with this deficiency during pre-testing of blood tests before any surgery.
Causes of Factor XII Deficiency
The causes of deficiency of factor XII are unique, for that onee must know the bleeding and clotting process. When bleeding happens, the body initiates a series of reactions that aids the blood clotting process. This series of reaction is termed as coagulation cascade. This process includes special proteins known as coagulation factors. Factor XII is one of the coagulation factors. Each factor in this chain triggers the other reaction and the final product that one gets by this coagulation cascade is the blood clot. Shortage of factor XII restricts bleeding. Hence, blood clot occurs but slowly. This disease is a rare inherited condition and is not fatal.
Symptoms and Treatments
This is not a big medical issue hence generally patient suffering from this disease does not show many symptoms. In addition, since the disease does not harm any body functions, treatment of factor XII is also not necessary. It generally heals by itself.
Diagnostic Tests for Factor XII Deficiency
Diagnosis is made by extended activated partial thromboplastin time (aPTT) test. Factor XII deficiency is detected when blood-clotting examinations are performed for routine testing.
Factor XII Assay: In this test, the blood is drawn from a vein, generally present inside the elbow or in the back portion of the hand. The portion is cleaned with the help of medical antiseptics, to maintain necessary hygiene while testing. An elastic wrapper is draped around the upper arm for the pressure to build up and to produce swelling in the vein. After this, the medical practitioner softly injects a needle in the swollen vein. The blood is collected in an airtight tube that is attached with the inserted needle. Then the elastic band is removed. After the blood is collected, then the needle is also removed and the punctured site is covered to stop excessive bleeding. In case of young children, a pointed tool called lancet can be used to pierce in the skin to make the area bleed. In this case, blood is collected in a small glass tube called pipette, or on slides for testing. A medicated bandage can be used to cover the pierced place to stop the bleeding process.
Partial thromboplastin time (PTT): In this process, a medical practitioner uses needle to take blood from the vein. The blood is collected in an airtight bottle. A bandage is used to cover the bleeding place.
Factor XII deficiency is not a big problem and does not affect any body functions. There is no treatment available, as medical field does not consider it as a dangerous condition unlike other hemic disorders.
Anda baru saja membaca artikel yang berkategori Causes /
deficiency /
Factor XII /
Symptoms /
Treatment
dengan judul Factor XII Deficiency Causes Symptoms and Treatments. Anda bisa bookmark halaman ini dengan URL https://medipub.blogspot.com/2011/04/factor-xii-deficiency-causes-symptoms_20.html. Terima kasih!
Ditulis oleh:
Unknown - Wednesday, 20 April 2011
